Defender of the people
Lexiss is a modern creative spelling of Alexis. It derives from the Greek verb alexein, which means to help or to defend, and was historically used as a masculine name before becoming a popular choice for girls.
Less common today
Lexiss isn't in the latest US Top 1000. It last peaked at #6,876 in 2003.
US births per 5-year period, 1990βpresent (SSA data).