Pearl or bitter; also associated with the month of May
Mayzie is primarily a playful diminutive of Margaret, meaning 'pearl,' or Mary, meaning 'bitter.' In modern usage, it is often treated as a creative variant of Maisie or a month-name derivative of May. It gained specific cultural recognition through the works of Dr. Seuss.
Less common today
Mayzie isn't in the latest US Top 1000. It last peaked at #2,048 in 2025.
A flamboyant and irresponsible bird · Seussical
United States Senator from Hawaii
US births per 5-year period, 1990–present (SSA data).
