Modern American creation, likely a blend of Derek and Leona
Dereona is a contemporary American name without a single ancient root. It is likely a creative feminine elaboration of the name Derek, meaning 'people's ruler,' combined with the suffix -ona, or a blend of Derek and Leona, which means 'lioness.'
Less common today
Dereona isn't in the latest US Top 1000. It last peaked at #4,733 in 2010.
US births per 5-year period, 1990βpresent (SSA data).