Defender of the people
Alyxis is a modern spelling variation of Alexis. It is derived from the Greek name Alexandros, specifically the verb 'alexein' which means to defend or protect. While the 'i' spelling is more common, the 'y' variant offers a contemporary, stylized look.
Less common today
Alyxis isn't in the latest US Top 1000. It last peaked at #5,230 in 1994.
US births per 5-year period, 1990βpresent (SSA data).