Defender of the people
Alixis is a modern spelling variation of Alexis. It is derived from the Greek verb 'alexein', which means to ward off or protect, historically used as a name for those who guard or defend.
Less common today
Alixis isn't in the latest US Top 1000. It last peaked at #10,143 in 1992.
US births per 5-year period, 1990βpresent (SSA data).