Of the Sixtus family; referring to the Sistine Chapel
Derived from the Latin name Sixtus, meaning 'sixth'. It is most famously associated with the Sistine Chapel in Vatican City, which was named after Pope Sixtus IV. In modern usage, it evokes the grandeur of Renaissance art and Italian heritage.
Less common today
Sistine isn't in the latest US Top 1000. It last peaked at #6,092 in 2025.
US births per 5-year period, 1990βpresent (SSA data).
American model and daughter of Sylvester Stallone
A main character in the novel The Tiger Rising Β· The Tiger Rising