Defender of mankind
Lexiana is a modern American elaboration of the name Lexi, which is a diminutive of Alexandra. It combines the strength of the Greek 'Alexo' (to defend) with the popular '-ana' suffix, creating a more formal and melodic version of a short nickname.
Less common today
Lexiana isn't in the latest US Top 1000. It last peaked at #7,959 in 2014.
US births per 5-year period, 1990βpresent (SSA data).