Follower of Christ or anointed one
A modern compound name blending Kristy, a diminutive of Christina, with the classic suffix Anna. It ultimately derives from the Greek word for 'anointed' and the Hebrew name for 'grace'.
Less common today
Kristyanna isn't in the latest US Top 1000. It last peaked at #10,568 in 2000.
US births per 5-year period, 1990βpresent (SSA data).