Slender or fair
Keyleen is a modern American invention, likely created as a phonetic blend of the name Kay or the prefix Key- with the popular Irish-inspired suffix -leen. It is often associated with the Irish name Caoilinn, which means slender or fair, or seen as a variation of Kayleen.
Less common today
Keyleen isn't in the latest US Top 1000. It last peaked at #8,853 in 2014.
US births per 5-year period, 1990βpresent (SSA data).