Pure, combination of Kay and Lise
Kaylise is a modern American invention, likely created by blending the name Kay, meaning 'pure', with Lise, a diminutive of Elizabeth meaning 'pledged to God'. It follows the contemporary trend of adding melodic suffixes like '-lise' or '-lyse' to established prefixes.
Less common today
Kaylise isn't in the latest US Top 1000. It last peaked at #11,494 in 2015.
US births per 5-year period, 1990βpresent (SSA data).