Pure or keeper of the keys
Kailene is a modern American elaboration of the name Kay or Kaia, often influenced by the Irish name Kayley or the Greek name Katherine. It combines the 'Kai' prefix with the popular 'lene' suffix, suggesting qualities of purity or guardianship.
Less common today
Kailene isn't in the latest US Top 1000. It last peaked at #5,394 in 1993.
US births per 5-year period, 1990βpresent (SSA data).