Combination of the prefix De and the name Andre
Deiondre is a modern American invention, likely created by blending the popular prefix 'De-' with the classic name Andre. Andre is the French form of Andrew, which ultimately derives from the Greek name Andreas, meaning 'manly' or 'strong'. It gained some visibility in the late 20th century alongside similar names like Deion and Deandre.
Less common today
Deiondre isn't in the latest US Top 1000. It last peaked at #1,906 in 1996.
NFL defensive back
US births per 5-year period, 1990βpresent (SSA data).