Unintelligible speakers
Derived from the Dakota word 'shaiyena', it was the name given by the Sioux to the Cheyenne people. It historically refers to those who speak a different language, specifically an Algonquian language. This specific spelling is a rare variation of the more common Cheyenne.
Less common today
Cheyene isn't in the latest US Top 1000. It last peaked at #2,347 in 1997.
US births per 5-year period, 1990βpresent (SSA data).